The current research aims to develop a theory in the field of organizational ambidexterity to better understand this phenomenon in the technology-based businesses of ACECR. The research strategy in the qualitative phase is based on grounded theory, and the data analysis method used in this research is the systematic approach (Strauss and Corbin's systematic model). Data collection was conducted through interviews. Accordingly, in the qualitative phase, 16 interviews were conducted with experts from ACECR's technology-based organizations, and 4 supplementary interviews were also conducted to achieve theoretical saturation. In the quantitative phase, the research method was descriptive-survey, and the data collection tool in this phase was a questionnaire. The results showed that organizational ambidexterity management was identified as the core category in this research. Its sub-concepts include ambidexterity structure management, innovative culture management, and ambidexterity processes management, which constituted the core category. Based on the obtained results, the causal conditions in this research are ambidextrous management and leadership, ambidextrous human resources, and multi-faceted structures. On the other hand, the contexts were organizational ambidexterity culture, upstream documents, and Jihadi culture. Furthermore, the strategies resulting from the grounded theory model are designing ambidextrous human resource processes, designing a technology commercialization model, designing an organizational ambidexterity evaluation system, and designing a resource allocation system. On the other hand, institutional communications in the field of science and technology and the organizational ambidexterity environment were identified as intervening factors. Finally, value creation, completion of the technology chain, organizational development, and organizational paradox management were the consequences identified and explained as factors influencing organizational ambidexterity in line with commercialization in technology-based organizations.